In the white paper “Evaluation of Hb NEXT, the A.Menarini Diagnostics new generation HPLC analyzer for HbA1c detection”, the results of analytical performance evaluation of Hb NEXT in comparison with six different reference systems for HbA1c testing are reported.
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Hb NEXT
- FEATURES
- TECHNICAL DATA
- PRODUCT CODES
- WHITE PAPER
- MULTIMEDIA
Hb NEXT is the new reversed-phase cation exchange HPLC analyzer designed to deliver precise and accurate quantification of HbA1c, HbA2, HbF and major hemoglobin variants. Drawing on more than 35 years of daily customer contact and support, Hb NEXT is the response to a need for greater flexibility, productivity and reliability. In ONE single analyzer your laboratory has the possibility to freely choose between the TWO analysis modes available: Variant mode to measure HbA1c for Diabetes management and Thalassemia mode for the hemoglobinopathies screening. Using the same column and all reagent containers installed, the operator can easily switch the analysis mode, giving your laboratory the power to decide between THREE different working methods according to need.
This cutting-edge, fully automated system combines HPLC precision and variant detection with the rapid throughput your laboratory needs. Hb NEXT offers high performance, user-friendly steps, and no sample preparation. Most importantly, it delivers results clinicians can trust.
FULL TRACEABILITY, FLEXIBILITY AND AUTOMATION
- Sample type automatically recognized with only 2 rack versions: whole blood/pre-hemolysed; anemic samples
- Automatic sample identification by tube rotation and barcode scanning
- Sample stirring by sample tube inversion
- Semi-automatic preparation of calibrators, controls and pre-hemolysed samples
- Identification and traceability of reagents through QR code reading
- Results are traceable to the IFCC reference method and reported in both IFCC (mmol/mol) and NGSP (%) units
USER FRIENDLY WITH EXTENDED AUTONOMY
- Possibility to load reagents in duplicate with automatic switch and management
- Full compatibility between different lots of eluents and column
- No need to change column and reagents when switching between modes
- Closed tube sampling for maximum safety to the operator
- Minimized operator intervention without daily maintenance
- High column lifetime with at least 6000 tests
- Loader capacity for 50 or 110 sample tubes
Brochure available HERE
Intended use
Quantification of HbA1c , HbA2, HbF and characterization of Hb variants
Samples
Human whole venous blood and pre-hemolysed samples
Measurement principle
HPLC - Reversed-phase cation exchange
Measurement unit
Peak calibration and result calculated in SI units (mmol/mol) - Conversion to NGSP % value via IFCC master equation
Measurement resolution
0.01 mmol/mol | 0.01%
Quantitative range
HbA1c: 9-195 mmol/mol, 3-20% | HbF: 0-100% | HbA2: 0-8% | Hb variants: 0-100%
Processing speed
Variant mode: 60 seconds per sample | Thalassemia mode: 380 seconds per sample
Warm-up time
< 10 minutes
Minimum sample volume
1 mL – standard whole blood containers | 300 μL – pre-diluted EP tubes
Sample consumption
(whole blood)
Variant mode: 3 μL | Thalassemia mode: 7 μL
Sample container
Whole blood sample tube: (12-15 mm diameter) × (75-100 mm height)
With mixing function active: (12.3-13.2 mm diameter) × (75-85 mm height)
Column lifetime
At least 6000 tests
Sample identification
Internal barcode reader
Sampler capacity
50 sample loader: 50 samples + STAT | 110 sample loader: 110 samples + STAT
Display and printer
10.1" TFT color LCD screen and thermal printer
Power supply and consumption
AC 100V~240V, 50-60 Hz, 250 VA
Dimensions and weight
66 kg and 722x730x729 mm (LxWxH) – 50 sampler loader
73 Kg and 722x873x729 mm (LxWxH) – 110 sampler loader
System operating environment
Temperature: 10-30 °C; humidity: 20-80% R.H. (no condensation)
Connectivity
LIS: RS-232, RJ45 Ethernet, bidirectional protocol
55607 | Hb NEXT Analyzer - 50 sample loader | 1 pcs |
55943 | Hb NEXT Analyzer - 110 sample loader | 1 pcs |
55599 | Hb NEXT Eluent A | 1x800 mL |
55600 | Hb NEXT Eluent B | 1x800 mL |
55601 | Hb NEXT Eluent C | 1x800 mL |
55602 | Hb NEXT Eluent D | 1x800 mL |
55603 | Hb NEXT Haemolysis solution H | 1x2500 mL |
55604 | Hb NEXT Column | 1 pcs |
55605 | Hb NEXT HbA1c Control | 2x0,1 mL |
55606 | Hb NEXT HbA1c Calibrator | 2x0,1 mL |
56149 | ß-THALASSAEMIA & HbA1c Calibrator | 2x0,1 mL |
56150 | ß-THALASSAEMIA & HbA1c Control Material | 2x0,1 mL |
UNAMAX is available in the following A.Menarini Diagnostics countries: